Conserved roles for yeast Rho1 and mammalian RhoA GTPases in clathrin-independent endocytosis
نویسندگان
چکیده
منابع مشابه
Conserved roles for yeast Rho1 and mammalian RhoA GTPases in clathrin-independent endocytosis
Eukaryotic cells use numerous endocytic pathways for nutrient uptake, protein turnover and response to the extracellular environment. While clathrin-mediated endocytosis (CME) has been extensively studied in yeast and mammalian cells, recent studies in higher eukaryotes have described multiple clathrin-independent endocytic pathways that depend upon Rho family GTPases and their effector protein...
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Yeast is a powerful model organism for dissecting the temporal stages and choreography of the complex protein machinery during endocytosis. The only known mechanism for endocytosis in yeast is clathrin-mediated endocytosis, even though clathrin-independent endocytic pathways have been described in other eukaryotes. Here, we provide evidence for a clathrin-independent endocytic pathway in yeast....
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ژورنال
عنوان ژورنال: Small GTPases
سال: 2012
ISSN: 2154-1248,2154-1256
DOI: 10.4161/sgtp.21631